Oferty pracy w projektach finansowanych przez NCN
Narodowe Centrum Nauki prezentuje bazę ogłoszeń o wolnych stanowiskach pracy przy projektach finansowanych przez Centrum. Narodowe Centrum Nauki nie ponosi odpowiedzialności za treść i wiarygodność przesyłanych ofert pracy.
Uprzejmie informujemy o nowych warunkach zatrudniania osób na stanowiska typu post-doc: limit czasu upływającego od uzyskania stopnia doktora dla aplikujących na te stanowiska kobiet może być przedłużony o 1,5 roku za każde urodzone bądź przysposobione dziecko.
Oferta pracy
Nazwa stanowiska: PhD student
Wymagania:
Required skills and qualifications
• Master's degree in biology, biotechnology, chemistry, or related science to be obtained latest by the end of September 2024
• Practical experience in the lab
• Fluency in written and spoken English
• Talented and motivated, with a passion for science
We are now offering a PhD student position to work on the project aimed at obtaining metallacarborane-containing peptides with potent activity against Gram-negative bacteria. The project addresses one of the most important problems facing the global society – antimicrobial resistance. Gram-negative bacteria are particularly difficult to treat and develop new antibiotics for. In the project, we will develop unique antimicrobial peptides and test their effectiveness on a variety of Gram-negative bacteria including clinical isolates. Detailed studies on the mechanism of action of the conjugates will allow us to uncover the processes underlying the observed biological effects and better understand how metallacarboranes interact with biomolecules and affect biological systems – crucial knowledge on the further development of metallacarboranes in biomedical applications. The implementation of this project will advance the field in terms of developing novel chemistry to design therapeutics and developing treatment options for difficult-to-treat infections.
Tasks
• Synthesis and characterization of metallacarborane-containing peptides
• Studies on the antibacterial activity of the peptides including their mechanism of action
• Studies on interactions of the peptides with lipid membranes and serum albumin
• Preparing publications and participation in scientific conferences
• Cooperation with other researchers in the group, ordering equipment and reagents
• Carrying out tasks resulting from the duties of a doctoral student at the Doctoral School
Termin składania ofert: 23 sierpnia 2024, 15:00
Forma składania ofert: dowolnie
Warunki zatrudnienia:
Our offer
• Cutting-edge research in an established group
• Doctoral scholarship for 4 years
• Comprehensive training in peptide synthesis, HPLC, LC-MS, microbiology studies, and physicochemical studies including circular and linear dichroism spectroscopy, ITC, light scattering, and electron microscopy
• Excellent research equipment including HPLC, mass spectrometry, CD spectropolarimeter, ITC, and electron microscopes
• Support for international mobility (3 – 6 months internships) and attendance at conferences
The doctoral scholarship will be paid for 4 years in the monthly amount of 4,076.53 PLN net (5,053.85 PLN gross) for the first two years and 4,739.52 PLN net (6,245.11 PLN gross) for the last two years, not lower than specified in the Law on Higher Education and Science and applicable executive regulations.
To apply, please visit https://www.intibs.pl/en/for-students/rules-of-recruitment/special-recruitment/special-recruitment-to-the-doctoral-school-for-phd-student-scholarship-holder-in-the-research-project-sonata-19-ncn-biological-sciences-application-deadline-23-08-2025.html
For additional information, please contact the principal investigator: Krzysztof Fink (krzysztof.fink@hirszfeld.pl)