Oferty pracy w projektach finansowanych przez NCN
Narodowe Centrum Nauki prezentuje bazę ogłoszeń o wolnych stanowiskach pracy przy projektach finansowanych przez Centrum. Narodowe Centrum Nauki nie ponosi odpowiedzialności za treść i wiarygodność przesyłanych ofert pracy.
Uprzejmie informujemy o nowych warunkach zatrudniania osób na stanowiska typu post-doc: limit czasu upływającego od uzyskania stopnia doktora dla aplikujących na te stanowiska kobiet może być przedłużony o 1,5 roku za każde urodzone bądź przysposobione dziecko.
Oferta pracy
Nazwa stanowiska: PhD student (SHENG4 project)
Wymagania:
1/2026. Special recruitment for the SD IITD PAN under the NCN-SHENG 4 research project “Chemical synthesis, immunological evaluation and epitope analysis of carbohydrate antigens of Pseudomonas aeruginosa “, in the discipline of Biological Sciences, announced on January 21, 2026. Number of places – 1.
Candidate profile
• master’s degree in biology, biotechnology, microbiology, or related fields
• strong motivation for research, scientific curiosity, and willingness to collaborate with national and international partners
• experience in laboratory work, including analytical techniques, microbiological and immunoenzymatic methods
• effective communication skills and practical knowledge of English
• teamwork skills, eagerness to teach and supervise students and interns
Research project description
Grant title: Chemical synthesis, immunological evaluation and epitope analysis of carbohydrate antigens of Pseudomonas aeruginosa (NSC grant)
Short description: Pseudomonas aeruginosa is an opportunistic pathogen that causes serious hospital-acquired infections in people with cystic fibrosis and severe burns. The World Health Organisation (WHO) has identified drug-resistant strains of this bacterium as a high-priority pathogen requiring the development of new bactericidal compounds. Although several vaccine candidates have entered clinical trials, the efficacy results of these preparations are insufficient and there is currently no approved vaccine against P. aeruginosa available. Lipopolysaccharide (LPS, O antigen) is one of the main surface antigens and virulence factors of this bacterium. To date, 20 major O serotypes (O1-O20) of P. aeruginosa have been identified. When designing vaccines based on O antigens, naturally isolated or synthetic polysaccharides can be used. In both cases, the antigen is selected based on its immunogenicity, and in the latter case, based on access to developed and efficient chemical synthesis procedures.
The project is based on Polish-Chinese cooperation. The Chinese partners will develop methods for synthesising new O antigens of defined length, while the Polish researchers will describe, as part of this doctoral project, how selected oligosaccharides in the form of glycoconjugates are processed and presented by antigen-presenting cells (APCs) of the immune system. Further exploration of these processes will contribute to the design of effective glycoconjugate vaccines.
We offer work in a dynamic, interdisciplinary and friendly team conducting research in the field of immunochemistry of bacterial sugar antigens.
LINK TO THE WEBSITE: https://hirszfeld.pl/en/structure/laboratories/laboratory-of-microbial-immunochemistry-and-vaccines/
Principal Investigator: Prof. Jolanta Łukasiewicz, the head of the Laboratory of Microbial Immunochemistry and Vaccines, jolanta.lukasiewicz@hirszfeld.pl (ORCID: 0000-0001-8081-7261)
PhD project description
Title: “Antigen processing and presentation studies of Pseudomonas aeruginosa selected O antigens”
Supervisor: Marta Kaszowska, PhD, Laboratory of Microbial Immunochemistry and Vaccines, marta.kaszowska@hirszfeld.pl (ORCID: 0000-0003-4469-5660).
A brief description of the work planned to be carried out as a part of PhD student research:
(i) preparation and structural characterisation of several defined glycoconjugates and their fluorescently labelled counterparts, including the natural O antigen and several selected fragments of P. aeruginosa O antigens with immunogenic peptides,
(ii) imaging of antigen presentation and processing in vitro using confocal microscopy,
(iii) characterisation of antigen-presenting cell differentiation using flow cytometry,
(iv) characterisation of CD4+ cells induced by the above-mentioned glycoconjugates.
The result of the research will be a correlation between the observed immunogenicity of glycoconjugates in vivo and the process of their ‘processing’ by immune system cells.
The doctoral project will enable the acquisition and development of a wide range of new research skills, including both the use of advanced equipment (NMR, mass spectrometry, SPR, GC-MS, HPLC, flow cytometry, serological methods) and the opportunity to develop one's own research ideas. We provide extensive support for professional development through internal and external training, individual mentoring, opportunities for development through cooperation with national and international centres, and the opportunity to participate in scientific conferences.
Place of PhD project: Poland, Wrocław, HIIET PAS, Laboratory of Microbial Immunochemistry and Vaccines in cooperation with the University of Life Sciences and PORT Polish Centre for Technology Development – Łukasiewicz Research Network.
PhD student responsibilities
1. Conducting scientific work and laboratory experiments covered by the doctoral project programme, including structural characterisation of glycoconjugates using NMR spectroscopy and mass spectrometry methods.
2. Conscientious performance of tasks.
3. Continuous scientific development and expansion of knowledge.
4. Presentation of results at national and international scientific conferences, participation in the preparation of manuscripts for publication and scientific research reports.
5. Implementation of the IITD PAN Doctoral School education programme.
Termin składania ofert: 17 lutego 2026, 00:00
Forma składania ofert: email
Warunki zatrudnienia:
Formal regulations regarding the scholarship
The PhD student-fellow will receive a scholarship for 48 months, which includes:
a) Year 1 and 2 (before mid-term evaluation): PLN 3,466.90 gross/month,
b) Year 3 and 4 (after mid-term evaluation): PLN 5,340.90 gross/month,
and an additional NSC research scholarship in the amount of PLN 1120 gross per month (for the period of 24 months).
https://szkoladoktorska.hirszfeld.pl/rekrutacja/aktualne-nabory/
Recruitment information Date of announcement: 21.01.2026 Application deadline: 17.02.2026 Interview: 24-25.02.2026 Start date of education: 1st March 2026 Scientific discipline: biological sciences Number of vacancies: 1 HIIET PAS website: hirszfeld.pl Doctoral School website: szkoladoktorska.hirszfeld.pl If no formally correct application is received within the stipulated time, the deadline for accepting applications may be extended.