Narodowe Centrum Nauki prezentuje bazę ogłoszeń o wolnych stanowiskach pracy przy projektach finansowanych przez Centrum. Narodowe Centrum Nauki nie ponosi odpowiedzialności za treść i wiarygodność przesyłanych ofert pracy.
Uprzejmie informujemy o nowych warunkach zatrudniania osób na stanowiska typu post-doc: limit czasu upływającego od uzyskania stopnia doktora dla aplikujących na te stanowiska kobiet może być przedłużony o 1,5 roku za każde urodzone bądź przysposobione dziecko.
• Bachelor's degree (Polish or foreign) in Biology, Biotechnology, Chemistry, or a related field.
• Current enrolment in a Master's programme in Biotechnology, Biology, or a related discipline.
• Ability to work in a team, creativity, attention to detail, and reliability in research work, as well as good interpersonal skills.
• Experience with molecular biology techniques, Real-Time PCR, and Western Blot will be an additional advantage.
• Basic programming skills (R, Python) will be an additional advantage.
Myocarditis is a serious cardiovascular disease. It can be caused by bacterial, parasitic, or viral infections, including COVID-19. Myocarditis may also have autoimmune origins. The disease frequently leads to dilated cardiomyopathy and myocardial damage. Diagnosis is hampered by its non-specific symptoms and the invasive nature of endomyocardial biopsy. Furthermore, the molecular mechanisms underlying the disease and its progression remain unknown. Metformin is a drug widely used in the treatment of type 2 diabetes. Little is known about its potential application in the treatment of myocarditis. Although recent studies suggest a cardioprotective effect of metformin in the course of myocarditis, the mechanisms governing this process have yet to be elucidated. To address the scientific objectives of this project, we will employ both standard and cutting-edge methods, including single-cell transcriptomics, spatial transcriptomics, and metabolomics. Using these techniques, we will characterize the effects of metformin at the single-cell level, enabling us to identify individual molecules as well as comprehensively describe the cell populations targeted by the drug — a remarkable advantage over currently used biological methods.
The research activities in which the candidate will participate will include:
• Single-cell and single-nuclei RNA sequencing data analysis
• Validation of analytical results using standard molecular biology techniques
• Performing molecular biology experiments, including Western Blot, RNA and protein isolation, and RT-qPCR
• Genotyping of transgenic mice
• Isolation of cardiac cells and preparation of sequencing libraries
• Analysis of metabolomic and transcriptomic data
• Histological and immunofluorescence staining of cardiac tissue
• Participation in the preparation of scientific publications and presentation of results at seminars and conferences
A scholarship for a period of 6 months from 01.06.2026, The scholarship amount will be 2000 PLN a month.
The scholarship will be paid in accordance with the resolution of the NSC Council no. 124/2022 of 1 December 2022 amending the Regulations for awarding NCN scholarships for NCN-funded research projects.
A scholarship contract will be signed with the selected Ph.D. student scholarship holder.
Required documents:
1) Curriculum vitae;
2) a motivation letter;
3) A copy of the graduation diploma;
4) Recommendations from the previous research supervisor;
5) Please attach the statement to the documents sent: I consent to the processing of my personal data for the purposes of the recruitment process.
6) List of scientific achievements (publications, conference communications, activities in a scientific circle);
Additional information:
Selected people will be individually invited to an interview. During the recruitment procedure, candidates may be asked to publicly present the results of their previous research in the form of a seminar delivered at the PULS.
The competition regulations are specified in the Resolution of the NSC Council no. 122/2022 of 1 December 2022.
Criteria for candidate evaluation:
1) the candidate’s research achievements, including publications in prestigious academic press /journals (50% of the final score);
2) research-related achievements, scholarships, awards and research experience gained in Poland or abroad, research workshops and training courses, participation in research projects (20% of the final score);
3) the candidate’s competence to carry out specific tasks in the research project (30% of the final score).
The competition committee will evaluate the candidates following the evaluation criteria specified above.
After the interview and evaluation of the candidates the competition committee will prepare a ranking list of the candidates together with their evaluation result, starting from the candidate who was awarded the highest score of points.
In case of questions please contact: email: monika.stefanska@up.poznan.pl