Oferty pracy w projektach finansowanych przez NCN

Nazwa jednostki: Institute of Biochemistry and Biophysics Polish Academy of Sciences – Warsaw, Inne oferty z tego miasta »
Nazwa stanowiska: PhD Student
Wymagania:

Skills/Qualifications:
Holding a degree of Master of Science [Magister], Master of Engineering [Magister Inżynier], medical doctor or equivalent in the field of: exact sciences, natural sciences, medical sciences or related disciplines, granted by a Polish or foreign university; a person who does not possess the qualifications described above may take part in the competition, but must obtain the qualifications in question and provide the relevant documents before the start of the programme at the Doctoral School (i.e., 1st October 2026). Education at the Doctoral School begins on 1st October 2026

Specific Requirements:
Excellent written and verbal communication skills in English.
Passion for science and a strong research interest.
Hands-on experience in molecular/cellular biology, tissue culture, and microscopy techniques would be an advantage.

Opis zadań:

Genome stability maintenance is fundamental for all living organisms. Cells are equipped with an array of DNA mechanisms ensuring prompt and faithful duplication of information encrypted in DNA. DNA, though, is prone to lesions induced by endogenous and exogenous sources. Although damaged DNA is rapidly targeted for repair, some of the lesions escape it and pose a threat, which is particularly dangerous to actively dividing cells. Lesions may block DNA replication, hampering thus cell division, which may cause cell death. As an alternative, cells can temporarily tolerate the damage in DNA, which permits the completion of the DNA duplication. In one of the DNA damage tolerance mechanisms, a special type of DNA polymerase is
employed to traverse the damage in a process named translesion synthesis (TLS). However, while permitting cell survival after DNA damage, their activity is often mutagenic and needs to be strictly controlled. A TLS
regulation is a multi-level process and depends largely on posttranslational modifications of engaged proteins and interactions between the proteins involved.

Our group is investigating the regulation and role of TLS polymerase iota, which is known as the most mutagenic human DNA polymerase. The necessity of tight governing of polymerase iota is underlined by the fact that both lack and overproduction of polymerase iota have been correlated with tumorigenesis. Posttranslational modifications and protein-protein interactions play a fundamental role in the regulation of
polymerase iota. Our previous studies showed that polymerase iota is a subject of p300-dependent acetylation. The project aims to reveal the mechanisms of regulation and the functional role of polymerase
iota acetylation. The proposed research will be conducted in healthy human and cancerous cell lines and extracellular systems. We will utilize a range of biochemical, microscopic, molecular biology, and bioinformatic techniques.

Typ konkursu NCN: OPUS – NZ
Termin składania ofert: 15 lipca 2026, 23:59
Forma składania ofert: email
Warunki zatrudnienia:

The recruitment process consists of three stages:
a) selection of candidates by the Committee based on the alignment of the candidate’s competencies with the requirements specified in the recruitment program;
b) selection of candidates by the Committee based on their previous achievements and academic results presented in the submitted documents;
c) an interview conducted by the Committee including in particular:
• a presentation delivered by the candidate containing the outcomes of his/her research (a Master’s thesis or other research work carried out by the candidate); the presentation must not last longer than 10 minutes;
• questions asked by the members of the Committee related to the presented project, the methods used and interpretation of the results obtained;
• questions asked by the members of the Committee related to the proposed PhD programme described in the recruitment announcement;
• questions related to the candidate’s motivation for scientific work.

Stage One
• education in the subject areas listed in the application guidelines; (scoring scale: 0.0 – 2.0 points);
• experience in the subject areas listed in the recruitment program (scoring scale: 0.0 – 2.0 points);
• other competencies specified in the recruitment program (scoring scale: 0.0 – 1.0 points).

Stage Two
• results obtained during studies (scoring scale: 0.0 – 4.0 points)
• competencies specified in the recruitment programme (scoring scale: 0.0 – 3.0 points)
• co-authorship of a scientific publication (depending on the role in the publication) (scoring scale: 0.0 –1.0 point)
• other achievements, e.g., awards, active conference attendance, honourable mentions, scholarships, domestic and foreign internships, voluntary work, popularisation of science (scoring scale: 0.0 – 2.0 points)

Stage Three:
• the degree of understanding of one’s own work; the ability to interpret the results obtained; the understanding of the methods used, knowledge in the field related
• to the topic of the submitted work (a scale of the evaluation: 0 - 10 points);
• knowledge in the subject matter listed in the recruitment announcement (a scale of the evaluation: 0 - 10 points);
• form of presentation of the candidate’s results (a scale of the evaluation: 0 - 3 points).

Dodatkowe informacje:

Benefits:
Possibility of renting a room in the Institute's hotel for the first 3 months at a special price (depending on rooms’ availability);
Possibility to join a medical plan;
Basic dental treatment;
Research mini-grants for doctoral students (up to PLN 20000, a PhD student may apply for funds twice during his/her studies);
Conference Grants (each PhD student can use up to PLN 12,000 to attend conferences during his/her studies);
Surcharge for the multi sport card;
Support in obtaining a temporary residence card (+ Reimbursement of TRC application expenses);
Language courses (Polish, English, German, French, Spanish, Italian… (the offer of courses may change);
Psychological care (up to 5 visits);
Subsidy for the purchase of eyeglasses (once every two years);
Free parking spot.

Website for additional job details:
https://ibb.edu.pl/en/phd-studies/rekrutacja/

Data dodania ogłoszenia: 2026-07-02 11:12:02