JPIAMR 13th Call Partner Search Tool

General Information

• Type: Partner looking for project
• Organisation: University of Buea
• Country: Cameroon (CM)

Research area

• Scientific area(s):
  1. Understand the impact of interventions on development and transmission of AMR
• One Health Setting:

  Human Health Animal Health Environment

• Keywords:

  methicillin-resistant Staphylococcus aureus; antimicrobial resistance; antimicrobial stewardship; resistance genes; one health

• Brief description of your expertise / expertise you are looking for:

  Our team is made up of a molecular biologist/biochemist, molecular Epidemiologist, Infectious Disease Specialist, community leaders, medical practitioners, poutltry/animal farmers, public health officials/policy makers. Community based/Public Engagement approach will be used to design, implement the project and to disseminate the results in order to maximise impact and uptake.

• Brief description of your project / the project you would like to join:

  The prevalence and the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) are constantly changing, with novel MRSA clones appearing in different geographical regions which can spread globally. Therefore, anti-infective/antimicrobial stewardship and infection prevention & control, continuous vigilance for MRSA through monitoring the characteristics, host specificity, and transmission routes of newer strains in different settings are required. Understating the molecular epidemiology of MRSA is therefore critical in assessing existing precautionary measures and planning appropriate prophylaxis to reduce the movement of amr through man, animals and the environment. The study will be a prospective cross-sectional, and multicenter study of risk factors associated with and prevalence of MRSA resistance and virulence genes covering isolates from children and adults in the Community, hospital settings, animals and plant materials, people involved in food production/handling and the environment. Hence we will be using a community-based and Public Engagement approach for the study. Methods will include antimicrobial stewardship, detection of resistance genes, virulence factors and statistical analysis over a period of two years. We aim to (1) decrypt the complex dynamics of selection and transmission of existing and new clones of multi drug resistant MRSA in Cameroon, and (2) Identify factors responsible for the tenacity and spread of resistant MRSA and resistance elements. The outcome will be (1) Slowing the emergence of multidrug resistant MRSA in community and hospital settings in Cameroon, (2) strengthening a One Health surveillance in Cameroon to fight multidrug MRSA resistance, (3) Improve collaboration and capacities with other countries for the prevention, surveillance and antibiotic research.

Dinga Jerome Nyhalah, PhD

• Organisation: University of Buea
• Position:
• E-mail: djnyhalah@yahoo.com