This is a match-making section for JPIAMR 13th call - One Health interventions to prevent or reduce the development and transmission of antimicrobial resistance (AMR).
Human Health
resistome; biomarkers of chronic colonization; human health; dysbiosis; microbiome
We can contribute to assess microbiome biomarkers associated with AMR colonization. We can use whole genome sequencing and metabolomic data to investigate microbiome biomarkers associated with long term colonization with Multi Drug Resistant (MDR) pathogens. We are able to investigate the metabolites produced by bacteria that may be involved in the inhibition of MDR resistant bacterial growth. We can also contribute to assess the impact of interventions (fecal microbiota transplantation, probiotic, prebiotics …) that can modulate bacterial population in an environment (gut, lung). We are able to use whole genome sequencing data that evaluate if an intervention induces dysbiosis in the microbiome, enriches or not the resistome. All the technics that we apply in human health can be easily translated to environmental or animal datasets.
Our team is interested in understanding the role of the microbiome in preventing the colonization by MDR pathogens.
Submitted on 2021-01-18 10:11:52
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