16th JPIAMR transnational call for research projects - AMR diagnostics and surveillance 2023 (DISTOMOS)

General Information

• Type: Partner looking for project
• Organisation: International Livestock Research Institute
• Country: Kenya (KE)
• Career stage: Early Career Researcher (up to 8 years** since PhD).

Research area

• Scientific area(s) of the call:
  1. Topic 2: to develop or improve existing strategies, technologies or methods, or data use strategies to support One Health AMR surveillance
• One Health Setting:

  Human Health

  Animal Health (incl. wild-life, livestock, acquatic organisms, and companion animals)
  Environment (incl. natural and built)

• Keywords:

  One Health; genomics; low income; surveillance; clinical outcomes

• Brief description of your expertise / expertise you are looking for:

  I am based at the International Livestock Research Institute, Nairobi, Kenya as a molecular epidemiologist on various projects investigating the epidemiology of Antimicrobial Resistance and other zoonoses. My background is in Veterinary medicine and a PhD in Molecular Epidemiology from the University of Edinburgh, UK. In a recently published study, we investigated the phylogeography of Escherichia coli from humans, livestock, and peri-domestic wildlife in 99 households across Nairobi, Kenya. https://www.nature.com/articles/s41564-022-01079-y . We found instances of strain sharing between humans and animals predominantly occurring within the household and shaped by host species. However, similarities in the resistome of the isolates did not match the patterns of shared genomes, and co-occurring ARGs were dispersed across the bacteria phylogeny indicative of putative transmission of plasmids between hosts. We also found interesting rates of AMR carriage in the isolates https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02677-7.

• Brief description of your project / the project you would like to join:

  I am interested in projects applying innovative approaches in studying diseases across human-animal-environment interfaces.

Dishon Muloi

• Organisation: International Livestock Research Institute
• Position: Epidemiologist
• E-mail: D.Muloi@cgiar.org
• Phone: 0725925615