17th JPIAMR transnational call for research projects - AMR Interventions 2024 (IMPACT)

General Information

• Project title: Cell-free biosynthesis and engineering of anti-fungals.
• Type: Project looking for partner
• Organisation: Queen Mary University of London
• Country: (UK)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Design novel or improved interventions to prevent, mitigate and /or treat fungal infections, which are resistant to treatments and/or are at risk of developing resistance
• Subtopics:

• One Health Setting:

  Human Health

  Animal Health (incl. wildlife, livestock, acquatic organisms, and companion animals)
  Plants (incl. trees and crops)

• Keywords:

  Synthetic biology; cell-free systems; natural products

• Brief description of your expertise / expertise you are looking for:

  My expertise is in the emerging area of cell-free synthetic biology. Am looking for prospective partners with either expertise in chemistry, natural products or bioinformatics that complement overall project.

• Brief description of your project / the project you would like to join:

  Use of cell-free systems for the rapid combinatorial expression and engineering of putative biosynthetic pathways that make anti-fungals. Key advantages include speed, automation and derivatization at microtitre scale, and expression of toxic molecules.

Simon Moore

• Organisation: Queen Mary University of London
• Position: Lecturer in synthetic biology
• E-mail: simon.moore@qmul.ac.uk
• Web: www.simonmoorelab.com