17th JPIAMR transnational call for research projects - AMR Interventions 2024 (IMPACT)

General Information

• Type: Partner looking for project
• Organisation: Technical University of Munich
• Country: Germany (DE)
• Career stage: Early Career Researcher (up to 8 years** since PhD).

Research area

• Scientific area(s) of the call:
  1. Topic 2: Improve and/or, compare and/or evaluate strategies, technologies, treatments, methods, protocols or data collection based on existing interventions, aiming to prevent or reduce the emergence or spread of antibacterial or antifungal resistance or to treat/cure infections caused by resistant bacteria/fungi and recommend new policies.
• Subtopics:
  1. Improve and/or compare and/ or evaluate the effectiveness of existing interventions (e.g. cost effectiveness clinical utility, socio-economic adaptability, reducing AMR emergence, spread, transmission, treatment etc.)
  2. Identify the barriers to uptake, including factors leading to the success or failure of previously run pilot interventions, and when applicable design solutions to overcome them.

• One Health Setting:

  Human Health

  Animal Health (incl. wildlife, livestock, acquatic organisms, and companion animals)
  Plants (incl. trees and crops)
  Environment (incl. natural and built)

• Keywords:

  Metabolomics; 13C-labeling methods; Metabolic flux; Metabolite profiling; Phytogenic compounds; NMR and GC

• Brief description of your expertise / expertise you are looking for:

  TUM partner studies metabolic pathways, and fluxes in various organisms, including pathogenic bacteria. It was and is a central focus of TUM to develop and assess new alternatives to antimicrobials. Based on the excellent NMR and MS equipment at TUM, Eisenreich and his co-workers contribute with their analytical expertise and techniques to determine the structures of bioactive compounds of new products. Thanks to our well-established isotope labeling and metabolomics techniques at TUM, the functionalities, and targets of new antimicrobials can be determined. We are also interested in studying metabolic pathways behind resistance, and persistance of ESKAPE.

• Brief description of your project / the project you would like to join:

  Metabolomics; 13C-labeling methods; Metabolic flux; Metabolite profiling; Phytogenic compounds; NMR, GC

Awad Shehata

• Organisation: Technical University of Munich
• Position: PD Dr
• E-mail: awad.shehata@tum.de
• Phone: +4917623378910