17th JPIAMR transnational call for research projects - AMR Interventions 2024 (IMPACT)

General Information

• Type: Partner looking for project
• Organisation: Rigas Stradins University
• Country: Latvia (LV)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 2: Improve and/or, compare and/or evaluate strategies, technologies, treatments, methods, protocols or data collection based on existing interventions, aiming to prevent or reduce the emergence or spread of antibacterial or antifungal resistance or to treat/cure infections caused by resistant bacteria/fungi and recommend new policies.
• Subtopics:
  1. Improve and/or compare and/ or evaluate the effectiveness of existing interventions (e.g. cost effectiveness clinical utility, socio-economic adaptability, reducing AMR emergence, spread, transmission, treatment etc.)

• One Health Setting:

  Human Health

  Environment (incl. natural and built)

• Keywords:

  systems biology and medicien; PBPK; popPK

• Brief description of your expertise / expertise you are looking for:

  Our systems biology oriented group (https://www.biosystems.lv/ ) has experience in mathematical modeling of different metabolic, transport and signaling processes to explain the experimentally observed process by the mechanisms of interactions of the involved elements. This way it is possible to test hypotheses, parametrize process parameters and select appropriate intervention strategies. Our group (https://www.biosystems.lv/) has experience in drug pharmacokinetics (NCA, popPK, PBPK) estimation and respective modeling and simulation approaches. We believe these capabilities could provide valuable insights into therapeutic regimen personalization and improvement.

• Brief description of your project / the project you would like to join:

  We have interest and experience in mathematical modeling of different metabolic, transport and signalling processes, as well pharmacometric modelling (NCA, popPK, PBPK) and simulations to explain the clinically either experimentally observed process by the mechanisms of interactions of the involved elements. This way it is possible to test hypotheses, parametrize process parameters and select appropriate intervention strategies.

Egils Stalidzans

• Organisation: Rigas Stradins University
• Position:
• E-mail: Janis.Kurlovics@rsu.lv
• Web: www.biosystems.lv/