17th JPIAMR transnational call for research projects - AMR Interventions 2024 (IMPACT)

General Information

• Type: Partner looking for project
• Organisation: Department of Bioengineering and iBB - Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa
• Country: Portugal (PT)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Design novel or improved interventions to prevent, mitigate and /or treat fungal infections, which are resistant to treatments and/or are at risk of developing resistance
• Subtopics:

• One Health Setting:

  Human Health

• Keywords:

  Candida drug resistance mechanisms evolution genome scale metabolic models drug target identification

• Brief description of your expertise / expertise you are looking for:

  The FunPath Lab, which I lead, is focused on understanding fungal infections caused by pathogenic yeasts of the Candida genus, on a genome-wide perspective, and on using this information to improve therapeutic options. My lab has 15 years of experience on characterizing new mechanisms of drug resistance in Candida, especially focused on transporters and transcription factor. We have also keen interest on understanding the genomic evolution of drug resistance acquisition, and using genome-scale models to identify promising new drug targets.

• Brief description of your project / the project you would like to join:

  Projects aiming to better characterize the molecular basis underlying the acquisition of drug resistance in fungal pathogens, to identify novel drug targets and novel drugs.

Miguel Cacho Teixeira

• Organisation: Department of Bioengineering and iBB - Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa
• Position: Professor
• E-mail: mnpct@tecnico.ulisboa.pt
• Phone: +351965161836
• Web: sites.google.com/view/ibb-tecnico-bsrg-funpath-lab/