17th JPIAMR transnational call for research projects - AMR Interventions 2024 (IMPACT)

General Information

• Type: Partner looking for project
• Organisation: Centre International de Recherche en Infectiologie
• Country: France (FR)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 2: Improve and/or, compare and/or evaluate strategies, technologies, treatments, methods, protocols or data collection based on existing interventions, aiming to prevent or reduce the emergence or spread of antibacterial or antifungal resistance or to treat/cure infections caused by resistant bacteria/fungi and recommend new policies.
• Subtopics:
  1. Improve and/or compare and/ or evaluate the effectiveness of existing interventions (e.g. cost effectiveness clinical utility, socio-economic adaptability, reducing AMR emergence, spread, transmission, treatment etc.)

• One Health Setting:

  Human Health

  Animal Health (incl. wildlife, livestock, acquatic organisms, and companion animals)

• Keywords:

  Acinetobacter baummannii; carbapenem resistance; genetics; horizontal gene transfer; genomics

• Brief description of your expertise / expertise you are looking for:

  Our lab focuses on the acquisition/transfer and identification of determinants of antibiotic resistance. We primarily study Acinetobacter baumannii and have assembled large collections of isolates in a One Health sampling program. We are using genome sequencing, statistical genetics (GWAS) but also microbiology and genetic approaches. We have developed methods to detect/quantify horizontal gene transfer events, including on multidrug resistant strains. We can perform conventional and high-throughput genetics (Tn-seq).

• Brief description of your project / the project you would like to join:

  We are interested in projects related to the identification of resistance mechanism, strategies to mitigate their HGT, assessing antibacterial activity of large panels of isolates. Focus should be on Acinetobacter baumannii.

Xavier Charpentier

• Organisation: Centre International de Recherche en Infectiologie
• Position:
• E-mail: xavier.charpentier@inserm.fr