17th JPIAMR transnational call for research projects - AMR Interventions 2024 (IMPACT)

General Information

• Type: Partner looking for project
• Organisation: University of Toronto
• Country: Canada (CA)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Design novel or improved interventions to prevent, mitigate and /or treat fungal infections, which are resistant to treatments and/or are at risk of developing resistance
• Subtopics:

• One Health Setting:

  Human Health

  Animal Health (incl. wildlife, livestock, acquatic organisms, and companion animals)

• Keywords:

  structural biology drug design protein biochemistry antimicrobials enzyme characterization

• Brief description of your expertise / expertise you are looking for:

  I\'m a structural biologist and biochemist with extensive expertise in studies of the molecular mechanisms of AMR and antimicrobial drug discovery. To a JPIAMR project, I can contribute recombinant protein production and characterization, structural biology (crystallography, cryo-electron microscopy), enyme-ligand interaction studies, structure-guided drug design and/or optimization, and bioinformatics (protein sequence family analysis, modeling/AlphaFold2, molecular dynamics, and function prediction)

• Brief description of your project / the project you would like to join:

  I am interested in joining a project with the goals of the discovery of new antimicrobials or modification of existing antimicrobials, studies of antimicrobial mechanism of action and mechanism of resistance, and characterization of drug targets/resistance enzymes. I am also interested in projects focused on discovery of new resistance enzymes/mechanisms, bioinformatics in terms of mechanisms of drug action and resistance, or related projects.

Peter Stogios

• Organisation: University of Toronto
• Position: Senior Research Associate
• E-mail: p.stogios@utoronto.ca
• Phone: 41694600982
• Web: biozone.utoronto.ca