17th JPIAMR transnational call for research projects - AMR Interventions 2024 (IMPACT)

General Information

• Type: Partner looking for project
• Organisation: A1 Chem Innovation GmbH
• Country: Germany (DE)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Design novel or improved interventions to prevent, mitigate and /or treat fungal infections, which are resistant to treatments and/or are at risk of developing resistance
• Subtopics:

• One Health Setting:

  Human Health

• Keywords:

  Photodynamic therapuetic intervention to tackle resistance microbes

• Brief description of your expertise / expertise you are looking for:

  I am an organic chemist and with expertise in making complex compounds. Looking for experts with antibacterial therapy and translational knowlédge.

• Brief description of your project / the project you would like to join:

  We have been working on different photosensitizers (PS), which produce cytotoxic reactive oxygen species (ROS) with an external light, so called photodynamic therapy (PDT). This PDT procedure is now established for antibacterial/antifungal therapy as well. To improve safety margin, as irradiating solely bacteria /Fungi is unachievable in humans, we fine-tuned the PS to make it inactive within human cells, but kept its phototoxicity intact in bacteria/fungi. Our first designed PS performed well in vitro studies, now we aim to expand this concept to translatable state with detail studies in vivo.

Srinivas Banala

• Organisation: A1 Chem Innovation GmbH
• Position: CEO
• E-mail: info@a1-chem.de
• Phone: 00492418096385
• Web: a1-chem.de