OHAMR Call for proposals 2026

General Information

• Type: Partner looking for project
• Organisation: Concordia University
• Country: Canada (CA)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Identify and develop new combination treatments using existing or innovative antimicrobials or antimicrobial with adjunctive treatments to extend drug efficacy and combat resistance.
• One Health Setting:

  H - Human Health

• Keywords:

  bacterial evolution; adaptive laboratory evolution; adjuvants; drug cycling; combination therapy

• Brief description of your expertise / expertise you are looking for:

  My lab has developed a lab evolution platform, SAGE, and used it in a series of publications for the high-throughput evolution of bacterial resistance. We have directly evolved resistance to \'evolution proof\' drugs, evolved antibiotic-susceptible bacteria purely through antibiotic exposure, and are experienced in the antimicrobial testing and evolution of clinical isolates. Well practiced in the growth/testing of lab strains and clinical isolates of E. coli, P. aeruginosa, S. enterica, Enterococcus gallinarum. Experience with whole genome sequencing, plasmid analysis, testing of S. aureus.

• Brief description of your project / the project you would like to join:

  -Discovery and characterization of new antibiotics. -Discovery and characterization of new methods of antimicrobial resistance. -Generation and study of resistance mechanisms, bacterial fitness. -Evolutionary pathway characterization. -Characterizing the evolutionary potential of new compounds, including those designed not to induce the evolution of antimicrobial resistance.

Brandon Findlay

• Organisation: Concordia University
• Position: Associate Professor
• E-mail: brandon.findlay@concordia.ca
• Web: findlaylab.ca