OHAMR Call for proposals 2026

General Information

• Type: Partner looking for project
• Organisation: University of Basel
• Country: Switzerland (CH)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Identify and develop new combination treatments using existing or innovative antimicrobials or antimicrobial with adjunctive treatments to extend drug efficacy and combat resistance.
• One Health Setting:

  H - Human Health

• Keywords:

  metabolomics chemical-genetic screens computational biology high-throughput large-scale

• Brief description of your expertise / expertise you are looking for:

  My research program centers on elucidating how metabolic regulation interfaces with genetic and pharmacological perturbations, integrating high-throughput experimental methods with advanced computational modeling. My group has developed new quantitative metabolomics techniques and scalable computational workflows that overcome key limitations of existing technologies, enabling large-scale functional inference of genes and the Mode of Action of uncharacterized compounds. By combining CRISPR-based perturbations, non-targeted metabolomics, and automated time-lapse microscopy, we developed a unique framework for dynamic metabolic profiling, yielding insights into drug–gene interactions, novel mechanisms of drug toxicity, and previously unrecognized functions of metabolic pathways.

• Brief description of your project / the project you would like to join:

  Use molecular profiling data to aid clinical decisions and predict optimal drug combinations

Mattia Zampieri

• Organisation: University of Basel
• Position: Associate Professor
• E-mail: mattia.zampieri@unibas.ch
• Phone: 0762208621
• Web: www.zampierilab.org/