This is a match-making section for OHAMR Call for proposals 2026.
H - Human Health
Structure-based drug design; Enzyme-based therapeutics; Biofilm; Advanced antimicrobial delivery systems
The Healthcare-Associated Infections Research Group aims to investigate the pathogenic mechanisms underlying some of the most prevalent infectious diseases in our setting, adopting a unified and integrative research framework that has been continuously developed since the 1980s. The group is part of I3PT, the research and innovation institute associated with Hospital Parc Taulí, a leading tertiary care hospital in Spain. This close connection between research and clinical practice enables strong translational impact, facilitating the study of infections from both molecular and clinical perspectives.
Our project, tentatively titled “Structure-based design of a novel antimicrobial agent against multidrug-resistant bacterial infection” aims to advance next-generation antimicrobial strategies through the development of enzyme-based therapeutics with enhanced efficacy against resistant bacteria. Our consortium comprises two Spanish research groups with strong and complementary expertise in protein structural biology and molecular/clinical microbiology. To strengthen the proposal, we are seeking European partners with specialized expertise in: 1) Biofilm biology and eradication strategies, 2) Nanoparticle- or vesicle-based delivery systems 3) Technologies or reagents to potentiate antimicrobial activity, 4) Advance platforms for the assessment and validation of novel antimicrobial compounds. We welcome collaborations in contributing to a competitive, high-impact proposal.
Submitted on 2025-12-17 12:55:02
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