OHAMR Call for proposals 2026

General Information

• Type: Partner looking for project
• Organisation: Institute of Microbiology AS CR
• Country: Czech Republic (CZ)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Identify and develop new combination treatments using existing or innovative antimicrobials or antimicrobial with adjunctive treatments to extend drug efficacy and combat resistance.
• One Health Setting:

  H - Human Health

• Keywords:

  antibiotic ribosome stress response

• Brief description of your expertise / expertise you are looking for:

  We offer expertise in working with ribosomes and ribosome-targeting antibiotics, ranging from the identification of ribosomal targets to structure-informed design of antibiotics that bind the ribosome. In our research we aim to define how ribosome arrest activates gene expression in an antibiotic-specific and concentration-dependent manner, and how bacteria use this antibiotic-mediated signaling to coordinate a stress response that leads to intrinsic resistance. We investigate the mechanisms of these antibiotics in clinically relevant models such as Staphylococcus, Clostridioides, and Mycobacterium species, thereby ensuring high translational applicability.

• Brief description of your project / the project you would like to join:

  Our laboratory seeks to actively participate in projects that implement ribosome-targeting antibiotics alongside investigations into stress-induced cellular responses that elicit intrinsic antibiotic resistance.

Gabriela Balíková Novotná

• Organisation: Institute of Microbiology AS CR
• Position: PI
• E-mail: gnovotna@biomed.cas.cz
• Phone: 608504301
• Web: lab111.mbu.cas.cz/