This is a match-making section for OHAMR Call for proposals 2026.
H - Human Health
A - Animal Health E - Environment3D in vitro models; extracellular matrix; biomaterials; bioprinting
Our research group specializes in the development of advanced 3D in vitro cellular models that faithfully replicate the architecture and function of human and animal tissues. These engineered systems provide physiologically relevant platforms for the evaluation of antibiotic efficacy and the study of antimicrobial resistance mechanisms under controlled, reproducible conditions. By integrating multiple cell types, extracellular matrix components, and biomimetic microenvironments, our models enable the assessment of drug responses and bacterial behavior in settings that more closely resemble in vivo scenarios than traditional 2D cultures. In parallel, we are actively developing sensing technologies that can be embedded within these 3D models. These include optical and polymer-based biosensors capable of detecting bacterial presence, activity, or metabolic changes directly within the tissue construct. Such sensors enable real-time, in situ monitoring and imaging of infection progression, opening new possibilities for studying host–pathogen interactions, tracking bacterial colonization, and evaluating treatment outcomes dynamically. Together, our expertise in 3D bioprinting, biomaterial engineering, and biosensing offers a robust platform for advancing antibiotic testing, improving predictive in vitro tools, and contributing to the understanding and mitigation of antimicrobial resistance
I aim to join a project that can use the 3D in vitro tissue models developed in our group as advanced platforms for antibiotic testing and for investigating the emergence of antimicrobial resistance.
Submitted on 2025-11-19 15:43:53
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