OHAMR Call for proposals 2026

General Information

• Type: Partner looking for project
• Organisation: Helmholtz center for infection research (HZI) and Hannover Medical School (MHH)
• Country: Germany (DE)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Identify and develop new combination treatments using existing or innovative antimicrobials or antimicrobial with adjunctive treatments to extend drug efficacy and combat resistance.
• One Health Setting:

  H - Human Health

  E - Environment

• Keywords:

  computational biology; GWAS; laboratory evolution; machine learning

• Brief description of your expertise / expertise you are looking for:

  We have a solid track record in the application of computational methods to large microbial genomes collections, in particular using statistical genetics (GWAS) and machine learning for the prediction of pathogenicity/virulence and AMR. We also have carried out work in developing new approaches for genomic epidemiology. We also have the ability to run in-vitro laboratory evolution experiments with large throughput, and have used it to study resistance to antisense-oligonucleotides (next generation antimicrobials).

• Brief description of your project / the project you would like to join:

  Either a project in which there is the need to leverage large genome collections and apply GWAS/machine learning to them, or to identify transmission chains through genomic epidemiology. We can also work with antisense-oligonucleotides in case a project would like to explore them as alternative treatments or adjuvants. Lastly, we can quickly run large scale laboratory evolution to test for mechanisms of resistance induced by treatments.

Marco Galardini

• Organisation: Helmholtz center for infection research (HZI) and Hannover Medical School (MHH)
• Position: Associate professor
• E-mail: galardini.marco@mh-hannover.de
• Web: www.microbial-pangenomes-lab.org/