This is a match-making section for OHAMR Call for proposals 2026.
H - Human Health
Antimicrobial resistance; Antimicrobial targets; Biofilm production; Phage research; Antimicrobial treatment
The Michael Ogon Laboratory for Orthopaedic Research (MOLOR) is based at the Orthopaedic Hospital Speising, one of Europe’s leading orthopaedic centres which performs more than 9,000 surgical procedures annually. MOLOR conducts cutting-edge basic and translational research aimed at improving the understanding and treatment of musculoskeletal disorders. One of the laboratory\'s primary research focuses is periprosthetic joint infection (PJI), one of the most challenging and complex complications in orthopaedics. MOLOR provides a unique research infrastructure, including a prospectively collected, ethics-approved musculoskeletal biobank with thousands of clinically well-characterised, consented human samples including periprosthetic synovial fluids and paired tissues collected from approximately 2000 hip and knee revision arthroplasty cases. This is complemented by an isolate collection of more than 2000 clinical strains, primarily from PJI cases, spanning a broad microbiological and antimicrobial resistance spectrum, each linked to extensive clinical metadata. The laboratory houses a fully equipped BSL-2 microbiology facility and a molecular biology laboratory, enabling integrated culture-based, molecular, and genomic analyses. MOLOR is an active partner in the Horizon Europe DRAIGON consortium (https://www.draigon.eu/), which aims to accelerate pathogen detection and antimicrobial resistance prediction in PJI through combined microbiological and molecular approaches. MOLOR’s research goals include characterizing the PJI microbial spectrum, elucidating antimicrobial resistance mechanisms, advancing understanding of biofilm biology, and investigating PJI aetiology and epidemiology, as well as exploring phage-based therapeutic approaches. MOLOR offers high-quality clinical materials, strong microbiology and molecular expertise, and robust collaborative capacity for multidisciplinary research consortia. The close academic collaboration between microbiologists, molecular biologists, and clinicians consistently translates into high-quality scientific publications.
MOLOR seeks partnerships that leverage its clinical samples, isolate collection, and microbiology/molecular expertise, with a strong translational focus. Key interests include characterizing the PJI microbial landscape, elucidating antibiotic resistance mechanisms, developing antimicrobial therapies, investigating biofilm biology and epidemiology, and exploring innovative strategies such as bacteriophage-based approaches.
Submitted on 2025-11-21 10:52:59
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