OHAMR Call for proposals 2026

General Information

• Type: Partner looking for project
• Organisation: The Hebrew University
• Country: Israel (IL)
• Career stage: Other.

Research area

• Scientific area(s) of the call:
  1. Topic 1: Identify and develop new combination treatments using existing or innovative antimicrobials or antimicrobial with adjunctive treatments to extend drug efficacy and combat resistance.
• One Health Setting:

  H - Human Health

  A - Animal Health
  P - Plants (Plant Health)

• Keywords:

  mycoviruses;potentiators;stress resistance

• Brief description of your expertise / expertise you are looking for:

  human fungal pathogens, fungal stress responses, mycoviruses, fungal immunology, medical mycology

• Brief description of your project / the project you would like to join:

  This project investigates how disrupting fungal stress-resistance systems can potentiate existing antifungal drugs. We focus on two stress-gated vulnerability nodes: (1) fungal regulated cell-death pathways (including apoptosis- and autophagy-like programs) whose activation can be pharmacologically triggered to amplify antifungal lethality, and (2) endogenous viral elements and mycoviruses that modulate stress tolerance, virulence, and drug susceptibility. By identifying stress-response effectors, death-pathway regulators, and virus-host interactions that buffer antifungal pressure, we aim to develop new adjuvant strategies that collapse fungal survival networks and restore or enhance antifungal efficacy.

Neta Shlezinger

• Organisation: The Hebrew University
• Position: Assistant Professor
• E-mail: neta.shlezinger1@mail.huji.ac.il
• Phone: +972515511377