JPIAMR 14th Call Partner Search Tool

General Information

• Type: Partner looking for project
• Organisation: IMDEA Nanociencia
• Country: Spain (ES)

Research area

• Scientific area(s) of the call:
  1. Design and implementation of new strategies (including optimisation of drug doses) for improved application, efficacy and delivery of single or combinations of antimicrobials
  2. Design and implementation of innovative tools, including novel chemistry and/or new materials for improved application, efficacy and delivery of antimicrobials
• One Health Setting:

  Human Health Animal Health (including wild-life, livestock, fishes, and companion animals)

• Type of studies/experimental approaches:

  in silico, in vitro, in vivo

• Keywords:

  advanced fluorescence microscopy; mechano-bactericidal materials; bacterial death processes

• Brief description of your expertise / expertise you are looking for:

  Our laboratory develops advanced fluorescence microscopy methods to study bacterial death processes at the single-cell level and with temporal resolution. We have developed labelling strategies to follow the effects of antimicrobial photodynamic therapy in real-time (Ortega et al, ACS Infectious Diseases 2022, 8, 86; Gollmer et al, Journal of Biophotonics 2017, 10, 264). Moreover, using combined fluorescence and atomic force microscopy, we have studied mechanically-induced bacterial death, which is relevant in the context of mechano-bactericidal nanomaterials, and quantified the forces involved in this process (del Valle et al, ACS Applied Materials & Interfaces, 2020, 12, 31235).

• Brief description of your project / the project you would like to join:

  I am particularly interested in studying mechanical effects on bacteria in the context of mechano-bactericidal strategies. These strategies may be purely physical, or as facilitators of the action of chemical antibiotics.

Cristina Flors

• Organisation: IMDEA Nanociencia
• Position: Senior Research Professor
• E-mail: cristina.flors@imdea.org
• Web: imdeananotools.wixsite.com/flors