JPIAMR 14th Call Partner Search Tool


This is a match-making section for JPIAMR 14th call - Disrupting drug Resistance Using Innovative Design (DRUID).

General Information

  • Type: Partner looking for project
  • Organisation: Sapienza University of Rome
  • Country: Italy (IT)

Research area

  • Scientific area(s) of the call:
    1. Optimisation of drug/plant protection agent combinations, alone or with adjunct therapies (including therapeutic vaccines)
    2. Design and implementation of innovative tools, including novel chemistry and/or new materials for improved application, efficacy and delivery of antimicrobials
  • One Health Setting:

    Human Health Animal Health (including wild-life, livestock, fishes, and companion animals) Plants (including trees and crops)

  • Type of studies/experimental approaches:

    in silico, in vitro, in vivo

  • Keywords:

    Antibiotic resistance; Bdellovibrio; microbiota; resistoma

  • Brief description of your expertise / expertise you are looking for:

    The group of research expertise (two researchers) embrace studies on antibiotic resistance and alternative or adjuvant strategies such as: bacterial predators; natural/synthetic substances and bacterial products; procedure concerning the transplantation of faecal microbiota for the treatment of antibiotic resistant Clostridium difficile colitis and other diseases related to gut dysbiosis.

  • Brief description of your project / the project you would like to join:

    Our research group would like to "join projects" concerning the study on antibiotics alternative strategies, for example the study of synthetic or natural compounds with antibiotic-adjuvant properties, or study on the use of bacterial predators such as Bdellovibrio bacteriovorus to overcome problems of antibiotic resistance. As "partner looking for project", we will have a multitasking approach that involves the use of innovative molecular and cellular approaches. We will be able to evaluate: a) The cytotoxicity towards different cell lines and their impact through the evaluation of the inflammatory induction levels by the evaluation of non-inflammatory and inflammatory cytokines; b) the MIC and MBC value against different bacterial species; c) the synergistic interaction activity between different antimicrobial substances; d) the bacterial biofilms features and antimicrobial resistances.

Contact details

Fabrizio Pantanella

Submitted on 2022-01-18 15:38:28

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