JPIAMR 14th Call Partner Search Tool

General Information

• Type: Partner looking for project
• Organisation: Dep. of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover, Foundation
• Country: Germany (DE)

Research area

• Scientific area(s) of the call:
  1. Improvement of drug/plant protection agent efficacy and/or specificity through chemical modifications (including hit to lead optimisation)
  2. Optimisation of drug/plant protection agent combinations, alone or with adjunct therapies (including therapeutic vaccines)
  3. Design and implementation of new strategies (including optimisation of drug doses) for improved application, efficacy and delivery of single or combinations of antimicrobials
  4. Design and implementation of innovative tools, including novel chemistry and/or new materials for improved application, efficacy and delivery of antimicrobials
• One Health Setting:

  Animal Health (including wild-life, livestock, fishes, and companion animals)

• Type of studies/experimental approaches:

  in silico, in vitro, in vivo preclinical and clinical studies in human and in all veterinary settings

• Keywords:

  antibiotic resistance microbiota drug-combinations commensal bacteria environmental contamination

• Brief description of your expertise / expertise you are looking for:

  We are a group of two researchers and provide expertise in studies on: a) antimicrobial resistance development in vitro; b) antimicrobial resistance development in vivo (pig, poultry, mice); c) MIC determination of different drug combinations in vitro/in vivo; d) antibiotic drug contaminations in the environment and possibilities of prevention; e) biofilm prevention in water supply of animals; f) biocompatibility of various compounds on mammal cell lines/primary cells, g) collection of field samples for determination of antimicrobial resistance in commensal isolates and pathogens.

• Brief description of your project / the project you would like to join:

  Our research group would like to join projects concerning a) synergistic effects of a combination of antibiotics with substances like plant extracts or synthetic compounds on commensal and/or pathogenic bacteria; b) development of novel dosage forms to diminish contaminations of the environment in farm animals; c) development of new dosage forms to optimize pharmacokinetic profils of drugs and drug combinations; d) optimization of drug dosage for lowering side effects on commensal bacteria. We are able to determine a) synergistic effects of drug-drug-combinations in vitro; b) synergistic effects of drug-drug-combinations in vivo (pigs); c) antimicrobial resistance development of different bacteria; d) environmental contaminations (drugs, bacteria), e) cytotoxic effects of substance combinations on various cell lines and primary cells; f) cytokine profiles of various cells.

Jessica Meißner

• Organisation: Dep. of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover, Foundation
• Position:
• E-mail: jessica.meissner@tiho-hannover.de
• Phone: +49 511 953 8723
• Web: www.tiho-hannover.de/kliniken-institute/institute/institut-fuer-pharmakologie-toxikologie-und-pharmazie/forschung/ag-meissner/forschungsschwerpunkt