JPIAMR 14th Call Partner Search Tool

This is a match-making section for JPIAMR 14th call - Disrupting drug Resistance Using Innovative Design (DRUID).

General Information

Scientific area(s) of the call:
1. Improvement of drug/plant protection agent efficacy and/or specificity through chemical modifications (including hit to lead optimisation)
2. Design and implementation of innovative tools, including novel chemistry and/or new materials for improved application, efficacy and delivery of antimicrobials
One Health Setting:
Human Health
Type of studies/experimental approaches:
in silico, in vitro, in vivo
Keywords:
Siderophore; Trojan Horse strategy;bacterial iron uptake systems; iron chelators
Brief description of your expertise / expertise you are looking for:
Our team is recognized in the design and the synthesis of bacterial siderophores and analogues and their therapeutic applications either as antibiotic vector (Trojan horse strategy) or as chelators to treat iron overload diseases. Expertise : Siderophore purification and characterization, organic chemistry, Mass Spectrometry and NMR analysis of organic compounds, conjugation chemistry.
Brief description of your project / the project you would like to join:
Project aiming to use a siderophore based Trojan horse strategy to improve the biological properties (antibiotic activity, toxicity, biodistribution, etc.) of antibacterial molecules on Gram-negative bacteria

Submitted on 2022-01-27 16:35:55