JPIAMR 14th Call Partner Search Tool

General Information

• Type: Partner looking for project
• Organisation: University of Latvia
• Country: Latvia (LV)

Research area

• Scientific area(s) of the call:
  1. Drug/plant protection agent repurposing
  2. Design and implementation of new strategies (including optimisation of drug doses) for improved application, efficacy and delivery of single or combinations of antimicrobials
• One Health Setting:

  Human Health Animal Health (including wild-life, livestock, fishes, and companion animals)

• Type of studies/experimental approaches:

  in silico, in vitro, in vivo

• Keywords:

  Pharmakokinetics Pharmacodynamics PBPK pop-PK artificial intelegence

• Brief description of your expertise / expertise you are looking for:

  We are developing and optimizing kinetic models of metabolism, pharmacokinetics, pharmacodynamics and signaling. We are interested in the development of mechanistic physiology-based pharmacokinetic (PBPK) modeling and extrapolation to clinical predictions from nonclinical and pre-clinical data, for example, to predict minimum inhibitory concentration (MIC). The repurposing research is based on computational approaches to the analysis of data of any type, such as gene expression, genotype or proteomic data or previous PD data.

• Brief description of your project / the project you would like to join:

  We are interested in the development of mechanistic physiology-based pharmacokinetic (PBPK) modeling and extrapolation to clinical predictions from nonclinical and pre-clinical data. Population based pharmacokietica anlyses, to investigate intra- or inter-individaul variabilities, as well as describe PK variables in population. The repurposing research based on computational approaches.

Egils Stalidzans

• Organisation: University of Latvia
• Position: Director
• E-mail: janis.kurlovics@lu.lv
• Web: www.biosystems.lv/pharmacokinetics