JPIAMR 14th Call Partner Search Tool

General Information

• Type: Partner looking for project
• Organisation: Université de Paris
• Country: France (FR)

Research area

• Scientific area(s) of the call:
  1. Improvement of drug/plant protection agent efficacy and/or specificity through chemical modifications (including hit to lead optimisation)
  2. Optimisation of drug/plant protection agent combinations, alone or with adjunct therapies (including therapeutic vaccines)
• One Health Setting:

  Human Health

• Type of studies/experimental approaches:

  in silico, in vitro, in vivo

• Keywords:

  Structural biology; chemistry; RND efflux pump; pseudomonas

• Brief description of your expertise / expertise you are looking for:

  Our laboratory is constituted of 7 teams with structural biologists and chemists. My team works on the comprehension of the assembly and function of RND efflux pumps from Pseudomonas aeruginosa.

• Brief description of your project / the project you would like to join:

  We would like to modify old EPIs. We propose to follow a drug-design approach combining structural biology, model, chemistry and affinity measures in vitro.

Dr. Broutin Isabelle

• Organisation: Université de Paris
• Position: team leader
• E-mail: isabelle.broutin@u-paris.fr
• Web: www.citcom.cnrs.fr/en/signaling-and-membrane-transport-group/